CD362 Gene ID | 6383 |
CD362 Official Full Name | syndecan 2 |
CD362 Alias | Syndecan-2, HSPG, SDC2 |
CD362 Cellular Expression | T; B; Endothelial; Epithelial; Granulocyte; Macrophage |
CD362 Ligand/Receptor/Association | fibronectin, TACI, IL-8 |
CD362 Function | Cell surface proteoglycan that bears heparan sulfate |
CD362 Summary | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008] |
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