CD371 Gene ID | 160364 |
CD371 Official Full Name | C-type lectin domain family 12 member A |
CD371 Alias | CLL-1, MICL, DCAL-2, CLEC12A |
CD371 Cellular Expression | Monocytes; granulocytes; NK |
CD371 Ligand/Receptor/Association | |
CD371 Function | cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response |
CD371 Summary | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011] |
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