CD66b Gene ID | 1088 |
CD66b Official Full Name | carcinoembryonic antigen related cell adhesion molecule 8 |
CD66b Alias | CD67, CGM6, CEACAM8 |
CD66b Cellular Expression | Granulocyte |
CD66b Ligand/Receptor/Association | CD66c |
CD66b Function | Cell adhesion and neutrophil activation |
CD66b Summary | The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008] |
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