CD75 Gene ID | 6480 |
CD75 Official Full Name | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
CD75 Alias | ST6GAL1, Sialyltransferase 1 |
CD75 Cellular Expression | T; B; Erythrocyte; Macrophage |
CD75 Ligand/Receptor/Association | CD22 |
CD75 Function | Functional maturation of B lymphocytes |
CD75 Summary | This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009] |
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