GDNF receptors and their cognate ligands are now recognized as one of the major neurotrophic networks in the nervous system, important for the development, maintenance and function of a variety of neurons and glial cells. As members of TGF-beta superfamily receptors, GDNF receptors take part in the control of multiple types of processes, from neuronal survival to axon guidance and synapse formation in the developing nervous system, to synaptic function and regenerative responses in the adult.
GDNF interacts to a multi-component receptor complex compound by ligand binding cell surface component GDNF receptor alpha1 (GFRα1) and signaling component rearranged during transfection (RET) receptor tyrosine kinase.
GDNF Receptor Products List
* Being developed. Tell us your requirement so that the products of interest be placed on the priority list.
- Receptors Classification
- Cytokine Receptors
- • Chemokine Receptor
- • Interferon/IFN Receptor
- • TNF Receptor
- • CSF Receptor
- • Interleukin Receptor
- • TGF-beta Superfamily Receptors
- - Activin Receptor
- - BMP Receptor
- - GDNF Receptor
- - TGF-beta Family Receptor
- Receptors by Differentiation Cells
- Receptors by Drug Target
- Receptors by Functions
- Receptors Reagent Products
- Receptors by Species
