Insulin-Like Growth Factor Receptor Overview

Insulin-like growth factor receptor (IGF receptor) is a cell surface receptor that is activated by a hormone called insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. IGF-1 receptor signaling enhances cell proliferation and transformation, allows us to understand that hyperinsulinemia and increased IGF-1 and IGF-2 concentrations may result in tumor growth.

IGF receptors are members of growth factor receptors and are implicated in several cancers, including breast, prostate, and lung cancers.

igf receptor

IGF Receptor Products List

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