Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.
A1CF protein expression
Widely expressed with highest levels in brain, liver, pancreas, colon and spleen.
A1CF cDNA / gene is a gene with protein product which located on 10q11.23. The A1CF gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 234 organisms have orthologs with human gene A1CF.