Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures.
A3GALT2 protein expression
Expressed in thymus and monocyte derived dendritic cells.
A3GALT2 cDNA / gene is a gene with protein product which located on 1p35.1. The A3GALT2 gene is conserved in Rhesus monkey, dog, cow, mouse, and rat. 125 organisms have orthologs with human gene A3GALT2.