Isoform 1: May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS).
ABCC6 protein expression
Expressed in kidney and liver. Very low expression in other tissues.
ABCC6 cDNA / gene is a gene with protein product which located on 16p13.11. The ABCC6 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken. 134 organisms have orthologs with human gene ABCC6.