ABCE1 Information: ABCE1 Protein, ABCE1 Antibody and ABCE1 Gene

ABCE1 Protein

ABCE1 protein function

Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.

ABCE1 protein expression


Activated by encephalomyocarditis virus (EMCV) and HIV-1.

ABCE1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

ABCE1 Gene

ABCE1 cDNA / gene is a gene with protein product which located on 4q31.21. The ABCE1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog. 236 organisms have orthologs with human gene ABCE1.