ABCG5 Information: ABCG5 Protein, ABCG5 Antibody and ABCG5 Gene

ABCG5 Gene family

ABCG5 Protein

ABCG5 protein function

ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane (PubMed:27144356). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11138003, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11138003, PubMed:15054092). The heterodimer with ABCG8 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).

ABCG5 protein expression

Tissue specificity

Strongly expressed in the liver, lower levels in the small intestine and colon.

ABCG5 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    651.00
  • Mass (KDa)
    72.00

ABCG5 Antibody

There are 1 ABCG5 antibodies which are validated in multiple tissues with various applications, including IHC-P. There are 1 ABCG5 antibody for IHC-P. Among all these ABCG5 antibodies, there are 1 anti-ABCG5 rabbit polyclonal antibodies . All the ABCG5 anbodies are produced in house and all are in stock. ABCG5 antibody customerized service is available.

ABCG5 Gene

ABCG5 cDNA / gene is a gene with protein product which located on 2p21. The ABCG5 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog. 241 organisms have orthologs with human gene ABCG5.