ACE Information: ACE Protein, ACE Antibody and ACE Gene

ACE Gene family

ACE Protein

ACE protein function

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.

ACE protein expression

Tissue specificity

Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.

Induction

Up-regulated in failing heart.

ACE protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    1,306.00
  • Mass (KDa)
    149.00

ACE Antibody

There are 2 ACE antibodies which are validated in multiple tissues with various applications, including IHC-P. There are 2 ACE antibody for IHC-P. Among all these ACE antibodies, there are 2 anti-ACE rabbit polyclonal antibodies . All the ACE anbodies are produced in house and all are in stock. ACE antibody customerized service is available.

ACE Gene

ACE gene / cDNA is a protein-coding gene which located on 17q23.3. The ACE gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, and frog.171 organisms have orthologs with human gene ACE.