Prostatic Acid Phosphatase Information: Prostatic Acid Phosphatase Protein, Prostatic Acid Phosphatase Antibody and Prostatic Acid Phosphatase Gene

Prostatic Acid Phosphatase Gene family

Prostatic Acid Phosphatase Protein

Prostatic Acid Phosphatase protein function

A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.; Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.

Prostatic Acid Phosphatase protein expression

Tissue specificity

Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer.

Prostatic Acid Phosphatase protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    386.00
  • Mass (KDa)
    44.00

Prostatic Acid Phosphatase Antibody

There are 10 Prostatic Acid Phosphatase antibodies which are validated in multiple tissues with various applications, including ELISA, WB, IHC-P, ELISA(Cap), ELISA(Det). There are 7 Prostatic Acid Phosphatase antibody for ELISA, 2 Prostatic Acid Phosphatase antibody for WB, 2 Prostatic Acid Phosphatase antibody for IHC-P, 1 Prostatic Acid Phosphatase antibody for ELISA(Cap), 1 Prostatic Acid Phosphatase antibody for ELISA(Det). Among all these Prostatic Acid Phosphatase antibodies, there are 2 anti-Prostatic Acid Phosphatase mouse monoclonal antibodies , 5 anti-Prostatic Acid Phosphatase rabbit monoclonal antibodies , 3 anti-Prostatic Acid Phosphatase rabbit polyclonal antibodies . All the Prostatic Acid Phosphatase anbodies are produced in house and all are in stock. Prostatic Acid Phosphatase antibody customerized service is available.

Prostatic Acid Phosphatase Gene

ACPP gene / cDNA is a protein-coding gene which located on 3q22.1. The ACPP gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, C.elegans, and frog.135 organisms have orthologs with human gene ACPP.