ACPT Information: ACPT Protein, ACPT Antibody and ACPT Gene

ACPT Gene family

ACPT Protein

ACPT protein function

May dephosphorylate receptor tyrosine-protein kinase ERBB4 and inhibits its ligand-induced proteolytic cleavage (PubMed:15219672). May play a role in odontogenesis (PubMed:27843125).

ACPT protein expression

Tissue specificity

Expressed mainly in the testis. Also expressed in the brain where they are enriched at the postsynaptic sites. Expressed at lower levels in the trachea, prostate, bone marrow, spinal cord, colon, fetal brain, heart, thymus, fetal liver, spleen, leukocytes, ovary, small intestine, pancreas and skeletal muscle. Expression is significantly lower in testicular cancer tissues than in normal testicular tissues. Isoform 3 is expressed in the testis, trachea, prostate and bone marrow.

Induction

Up-regulated by mibolerone (a synthetic androgen) and dihydrotestosterone (DHT) and is down-regulated by estrogen and progestin.

ACPT protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    426.00
  • Mass (KDa)
    46.00

ACPT Gene

ACP4 cDNA / gene is a gene with protein product which located on 19q13.33. The ACP4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and frog. 113 organisms have orthologs with human gene ACP4.