ADAM12 Information: ADAM12 Protein, ADAM12 Antibody and ADAM12 Gene

ADAM12 Gene family

ADAM12 Protein

ADAM12 protein function

Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity). {ECO:0000250}.

ADAM12 protein expression

Tissue specificity

Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.

ADAM12 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

ADAM12 Antibody

There are 7 ADAM12 antibodies which are validated in multiple tissues with various applications, including ELISA, WB, IP, IHC-P, ICC/IF. There are 4 ADAM12 antibody for ELISA, 1 ADAM12 antibody for WB, 1 ADAM12 antibody for IP, 1 ADAM12 antibody for IHC-P, 1 ADAM12 antibody for ICC/IF. Among all these ADAM12 antibodies, there are 1 anti-ADAM12 mouse monoclonal antibodies , 2 anti-ADAM12 rabbit monoclonal antibodies , 4 anti-ADAM12 rabbit polyclonal antibodies . All the ADAM12 anbodies are produced in house and all are in stock. ADAM12 antibody customerized service is available.

ADAM12 Gene

ADAM12 gene / cDNA is a protein-coding gene which located on 10q26.2. The ADAM12 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, and frog.215 organisms have orthologs with human gene ADAM12.