ADAM2 Information: ADAM2 Protein, ADAM2 Antibody and ADAM2 Gene

ADAM2 Gene family

ADAM2 Protein

ADAM2 protein function

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.

ADAM2 protein expression

Tissue specificity

Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.

ADAM2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

ADAM2 Gene

ADAM2 cDNA / gene is a gene with protein product which located on 8p11.22. The ADAM2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. 88 organisms have orthologs with human gene ADAM2.