ADAM9 Information: ADAM9 Protein, ADAM9 Antibody and ADAM9 Gene

ADAM9 Gene family

ADAM9 Protein

ADAM9 protein function

Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins. {ECO:0000250|UniProtKB:Q61072}.; Isoform 2: May act as alpha-secretase for amyloid precursor protein (APP). {ECO:0000269|PubMed:12054541}.

ADAM9 protein expression

Tissue specificity

Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart.

ADAM9 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

ADAM9 Gene

ADAM9 gene / cDNA is a protein-coding gene which located on 8p11.22. The ADAM9 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.214 organisms have orthologs with human gene ADAM9.