ADAMDEC1 Information: ADAMDEC1 Protein, ADAMDEC1 Antibody and ADAMDEC1 Gene

ADAMDEC1 Protein

ADAMDEC1 protein function

May play an important role in the control of the immune response and during pregnancy.

ADAMDEC1 protein expression

Tissue specificity

Expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.

Induction

Induced during DC maturation and up-regulated in response to T-cell signals. In macrophage up-regulated by bacterial lipopolysaccharides (LPS). Up-regulated by 1-alpha,25-dihydroxyvitamin D3 during differentiation of primary monocyte into macrophage.

ADAMDEC1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    470.00
  • Mass (KDa)
    52.00

ADAMDEC1 Gene

ADAMDEC1 cDNA / gene is a gene with protein product which located on 8p21.2. The ADAMDEC1 gene is conserved in chimpanzee, Rhesus monkey, dog, and mouse. 113 organisms have orthologs with human gene ADAMDEC1.