ADAMTS1 Information: ADAMTS1 Protein, ADAMTS1 Antibody and ADAMTS1 Gene

ADAMTS1 Gene family

ADAMTS1 Protein

ADAMTS1 protein function

Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.

ADAMTS1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)


ADAMTS1 cDNA / gene is a gene with protein product which located on 21q21.3. The ADAMTS1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 241 organisms have orthologs with human gene ADAMTS1.