Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity.
ADAMTS14 protein expression
Expressed in retina and at low levels in brain, lung and placenta. High expression in fetal tissues.
ADAMTS14 cDNA / gene is a gene with protein product which located on 10q22.1. The ADAMTS14 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog. 203 organisms have orthologs with human gene ADAMTS14.