Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis.
ADAMTS2 protein expression
Expressed at high level in skin, bone, tendon and aorta and at low levels in thymus and brain.
ADAMTS2 cDNA / gene is a gene with protein product which located on 5q35.3. The ADAMTS2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 186 organisms have orthologs with human gene ADAMTS2.