ADCY10 Information: ADCY10 Protein, ADCY10 Antibody and ADCY10 Gene

ADCY10 Gene family

ADCY10 Protein

ADCY10 protein function

Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed:17591988).

ADCY10 protein expression

Tissue specificity

Detected in airway epithelial cells and testis (at protein level) (PubMed:17591988). Weakly expressed in multiple tissues. Expressed in brain, heart, kidney, liver, lung, pancreas, peripheral blood leukocytes, placenta, skeletal muscle, stomach, thymus, airway epithelial cells, duodenum, jejunum and ileum. Very low level of expression in bone.

ADCY10 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

ADCY10 Gene

ADCY10 cDNA / gene is a gene with protein product which located on 1q24.2. The ADCY10 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and mosquito. 148 organisms have orthologs with human gene ADCY10.