ADHFE1 Information: ADHFE1 Protein, ADHFE1 Antibody and ADHFE1 Gene

ADHFE1 Gene family

ADHFE1 Protein

ADHFE1 protein function

Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.

ADHFE1 protein expression

Tissue specificity

Only expressed in adult liver.

ADHFE1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)


ADHFE1 cDNA / gene is a gene with protein product which located on 8q13.1. The ADHFE1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, M.oryzae, N.crassa, and frog. 241 organisms have orthologs with human gene ADHFE1.