Adiponectin Receptor 1 Information: Adiponectin Receptor 1 Protein, Adiponectin Receptor 1 Antibody and Adiponectin Receptor 1 Gene

Adiponectin Receptor 1 Gene family

Adiponectin Receptor 1 Protein

Adiponectin Receptor 1 protein function

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).

Adiponectin Receptor 1 protein expression

Tissue specificity

Widely expressed (PubMed:16044242). Highly expressed in heart and skeletal muscle (PubMed:12802337). Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337). Weakly expressed in colon, thymus and small intestine (PubMed:12802337).

Adiponectin Receptor 1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    375.00
  • Mass (KDa)
    42.00

Adiponectin Receptor 1 Gene

ADIPOR1 cDNA / gene is a gene with protein product which located on 1q32.1. The ADIPOR1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, rice, and frog. 220 organisms have orthologs with human gene ADIPOR1.