Adiponectin Receptor 2 Information: Adiponectin Receptor 2 Protein, Adiponectin Receptor 2 Antibody and Adiponectin Receptor 2 Gene

Adiponectin Receptor 2 Gene family

Adiponectin Receptor 2 Protein

Adiponectin Receptor 2 protein function

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity).

Adiponectin Receptor 2 protein expression

Tissue specificity

Ubiquitous (PubMed:16044242). Highly expressed in skeletal muscle, liver and placenta (PubMed:12802337). Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung (PubMed:12802337).

Adiponectin Receptor 2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    386.00
  • Mass (KDa)
    43.00

Adiponectin Receptor 2 Gene

ADIPOR2 cDNA / gene is a gene with protein product which located on 12p13.33. The ADIPOR2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, A.thaliana, and rice. 217 organisms have orthologs with human gene ADIPOR2.