ADIRF Information: ADIRF Protein, ADIRF Antibody and ADIRF Gene

ADIRF Protein

ADIRF protein function

Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin.

ADIRF protein expression

Tissue specificity

Expressed in adipose tissue (at protein level). Highly expressed in omental and subcutaneous adipose tissues. Expressed in heart, cornea, liver, kidney and spleen.

Induction

Up-regulated during pre-adipocyte differentiation. Up-regulated following DNA damage induced by UV irradiation.

ADIRF protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    76.00
  • Mass (KDa)
    7.00

ADIRF Gene

ADIRF cDNA / gene is a gene with protein product which located on 10q23.2. The ADIRF gene is conserved in chimpanzee, dog, and cow. 143 organisms have orthologs with human gene ADIRF.