Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
AGBL2 protein sequence
This sequence information is just for reference only.From Uniport
AGBL2 cDNA / gene is a gene with protein product which located on 11p11.2. The AGBL2 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, and frog. 168 organisms have orthologs with human gene AGBL2.