AGBL4 Information: AGBL4 Protein, AGBL4 Antibody and AGBL4 Gene

AGBL4 Gene family

AGBL4 Protein

AGBL4 protein function

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.

AGBL4 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

AGBL4 Gene

AGBL4 cDNA / gene is a gene with protein product which located on 1p33. The AGBL4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, and frog. 188 organisms have orthologs with human gene AGBL4.