AGBL5 Information: AGBL5 Protein, AGBL5 Antibody and AGBL5 Gene

AGBL5 Gene family

AGBL5 Protein

AGBL5 protein function

Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS.

AGBL5 protein expression

Tissue specificity

Expressed in brain.

AGBL5 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    886.00
  • Mass (KDa)
    97.00

AGBL5 Gene

AGBL5 cDNA / gene is a gene with protein product which located on 2p23.3. The AGBL5 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, and frog. 223 organisms have orthologs with human gene AGBL5.