AGO3 Information: AGO3 Protein, AGO3 Antibody and AGO3 Gene

AGO3 Gene family

AGO3 Protein

AGO3 protein function

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713). {ECO:0000255|HAMAP-Rule:MF_03032, ECO:0000269|PubMed:18771919, ECO:0000269|PubMed:23064648, ECO:0000269|PubMed:29040713}.

AGO3 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

AGO3 Antibody

There are 1 AGO3 antibodies which are validated in multiple tissues with various applications, including IHC-P. There are 1 AGO3 antibody for IHC-P. Among all these AGO3 antibodies, there are 1 anti-AGO3 rabbit polyclonal antibodies . All the AGO3 anbodies are produced in house and all are in stock. AGO3 antibody customerized service is available.

AGO3 Gene

AGO3 gene / cDNA is a protein-coding gene which located on 1p34.3. The AGO3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, rice, and frog.121 organisms have orthologs with human gene AGO3.