AGPAT3 Information: AGPAT3 Protein, AGPAT3 Antibody and AGPAT3 Gene

AGPAT3 Gene family

AGPAT3 Protein

AGPAT3 protein function

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA (PubMed:21173190). Has a preference for arachidonoyl-CoA as a donor. Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity).

AGPAT3 protein expression

Tissue specificity

Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver.

AGPAT3 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    376.00
  • Mass (KDa)
    43.00

AGPAT3 Gene

AGPAT3 cDNA / gene is a gene with protein product which located on 21q22.3. The AGPAT3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana, and frog. 233 organisms have orthologs with human gene AGPAT3.