AGTRAP Information: AGTRAP Protein, AGTRAP Antibody and AGTRAP Gene

AGTRAP Protein

AGTRAP protein function

Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.

AGTRAP protein expression

Tissue specificity

Ubiquitous but more abundant in kidney, heart, pancreas and thyroid.

AGTRAP protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    159.00
  • Mass (KDa)
    17.00

AGTRAP Gene

AGTRAP cDNA / gene is a gene with protein product which located on 1p36.22. The AGTRAP gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 233 organisms have orthologs with human gene AGTRAP.