AKR1A1 Information: AKR1A1 Protein, AKR1A1 Antibody and AKR1A1 Gene

AKR1A1 Gene family

AKR1A1 Protein

AKR1A1 protein function

Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). {ECO:0000269|PubMed:10510318, ECO:0000269|PubMed:11306097, ECO:0000269|PubMed:18276838}.

AKR1A1 protein expression

Tissue specificity

Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.

AKR1A1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

AKR1A1 Antibody

There are 1 AKR1A1 antibodies which are validated in multiple tissues with various applications, including ELISA. There are 1 AKR1A1 antibody for ELISA. Among all these AKR1A1 antibodies, there are 1 anti-AKR1A1 rabbit polyclonal antibodies . All the AKR1A1 anbodies are produced in house and all are in stock. AKR1A1 antibody customerized service is available.

AKR1A1 Gene

AKR1A1 gene / cDNA is a protein-coding gene which located on 1p34.1. The AKR1A1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, S.pombe, M.oryzae, N.crassa, A.thaliana, and frog.237 organisms have orthologs with human gene AKR1A1.