AKR1A1 Protein Overview: Sequence, Structure, Function and Protein Interaction

AKR1A1 Protein Overview

Aldehyde reductase (EC 1.1.1.2) and aldose reductase (EC 1.1.1.21; 103880) are monomeric NADPH-dependent oxidoreductases having wide substrate specificities for carbonyl compounds (summary by Bohren et al., 1989).

AKR1A1 protein family

Belongs to the aldo/keto reductase family.

AKR1A1 protein name

Recommended name
Alcohol dehydrogenase [NADP
Aliases
aldehyde reductase, ALR, DD3, dihydrodiol dehydrogenase 3
Alternative name
Aldehyde reductase Aldo-keto reductase family 1 member A1

AKR1A1 Gene family protein

Aldo-keto reductases

AKR1A1 Protein Sequence

Species Human AKR1A1 protein
Length 325
Mass (Da) 36573
Sequence Human AKR1A1 protein sequence
Species Mouse AKR1A1 protein
Length 325
Mass (Da) 36587
Sequence Mouse AKR1A1 protein sequence
Species Rat AKR1A1 protein
Length 325
Mass (Da) 36506
Sequence Rat AKR1A1 protein sequence

AKR1A1 Protein Molecular Weight & PI

Alcohol dehydrogenase [NADP(+)] (EC 1.1.1.2) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1)Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 2-325 Alcohol dehydrogenase [NADP(+)].

Molecular weight (Da)

36441.85

Theoretical pI

6.35

AKR1A1 Protein Structure

ALDEHYDE REDUCTASE
Deposited
1994-09-06   Released:  1996-06-20
Deposition Author(s)
El-Kabbani, O.
Organism(s)
Homo sapiens
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.4800 Å
R-Value Work
0.190
2ALR From PDB

Human AKR1A1 protein Secondary structure

AKR1A1 Protein Interaction

Recombinant AKR1A1 Protein Feature

AKR1A1 Protein, Human, Recombinant (His Tag)

High Purity
> 90 % as determined by SDS-PAGE
Low Endotoxin
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