AKR1C2 Information: AKR1C2 Protein, AKR1C2 Antibody and AKR1C2 Gene

AKR1C2 Gene family

AKR1C2 Protein

AKR1C2 protein function

Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. {ECO:0000269|PubMed:15929998, ECO:0000269|PubMed:17034817, ECO:0000269|PubMed:17442338, ECO:0000269|PubMed:8573067}.

AKR1C2 protein expression

Tissue specificity

Expressed in fetal testes. Expressed in fetal and adult adrenal glands.

AKR1C2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

AKR1C2 Gene

AKR1C2 gene / cDNA is a protein-coding gene which located on 10p15.1. The AKR1C2 gene is conserved in chimpanzee, Rhesus monkey, mouse, rat, and A.thaliana..