Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
AKR7A3 protein expression
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
AKR7A3 cDNA / gene is a gene with protein product which located on 1p36.13. The AKR7A3 gene is conserved in chimpanzee, Rhesus monkey, rat, M.oryzae, and N.crassa. 9 organisms have orthologs with human gene AKR7A3.