ALG10B Information: ALG10B Protein, ALG10B Antibody and ALG10B Gene

ALG10B Gene family

ALG10B Protein

ALG10B protein function

Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity). When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 (PubMed:14525949). Has a role in maintenance of cochlear outer hair cell function (By similarity).

ALG10B protein expression

Tissue specificity

Highly expressed in heart, placenta, liver, kidney and pancreas. Weakly expressed in lung, skeletal muscle and brain.

ALG10B protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    473.00
  • Mass (KDa)
    55.00

ALG10B Gene

ALG10B cDNA / gene is a gene with protein product which located on 12q12. The ALG10B gene is conserved in chimpanzee, Rhesus monkey, and C.elegans. 10 organisms have orthologs with human gene ALG10B.