ALK-1 Information: ALK-1 Protein, ALK-1 Antibody and ALK-1 Gene

ALK-1 Gene family

ALK-1 Protein

ALK-1 protein function

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. {ECO:0000269|PubMed:22718755, ECO:0000269|PubMed:22799562, ECO:0000269|PubMed:26176610}.

ALK-1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

ALK-1 Antibody

There are 9 ALK-1 antibodies which are validated in multiple tissues with various applications, including ELISA, ELISA(Det), ELISA(Cap), WB, IP, IHC-P. There are 7 ALK-1 antibody for ELISA, 1 ALK-1 antibody for ELISA(Det), 1 ALK-1 antibody for ELISA(Cap), 3 ALK-1 antibody for WB, 1 ALK-1 antibody for IP, 1 ALK-1 antibody for IHC-P. Among all these ALK-1 antibodies, there are 1 anti-ALK-1 mouse monoclonal antibodies , 4 anti-ALK-1 rabbit monoclonal antibodies , 4 anti-ALK-1 rabbit polyclonal antibodies . All the ALK-1 anbodies are produced in house and all are in stock. ALK-1 antibody customerized service is available.

ALK-1 Gene

ACVRL1 gene / cDNA is a protein-coding gene which located on 12q13.13. The ACVRL1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.165 organisms have orthologs with human gene ACVRL1.