alpha Actinin 4/ACTN4 Information: alpha Actinin 4/ACTN4 Protein, alpha Actinin 4/ACTN4 Antibody and alpha Actinin 4/ACTN4 Gene

alpha Actinin 4/ACTN4 Gene family

alpha Actinin 4/ACTN4 Protein

alpha Actinin 4/ACTN4 protein function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778).

alpha Actinin 4/ACTN4 protein expression

Tissue specificity

Widely expressed.

alpha Actinin 4/ACTN4 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    911.00
  • Mass (KDa)
    104.00

alpha Actinin 4/ACTN4 Antibody

There are 1 alpha Actinin 4/ACTN4 antibodies which are validated in multiple tissues with various applications, including WB, IHC-P, IP. There are 1 alpha Actinin 4/ACTN4 antibody for WB, 1 alpha Actinin 4/ACTN4 antibody for IHC-P, 1 alpha Actinin 4/ACTN4 antibody for IP. Among all these alpha Actinin 4/ACTN4 antibodies, there are 1 anti-alpha Actinin 4/ACTN4 rabbit polyclonal antibodies . All the alpha Actinin 4/ACTN4 anbodies are produced in house and all are in stock. alpha Actinin 4/ACTN4 antibody customerized service is available.

alpha Actinin 4/ACTN4 Gene

ACTN4 cDNA / gene is a gene with protein product which located on 19q13.2. The ACTN4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, S.pombe, M.oryzae, N.crassa, and frog. 164 organisms have orthologs with human gene ACTN4.