Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans (PubMed:10430883). Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct (PubMed:10430883). May protect against inflammation-associated gastric adenocarcinomas (By similarity).
A4GNT cDNA / gene is a gene with protein product which located on 3q22.3. The A4GNT gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog. 186 organisms have orthologs with human gene A4GNT.