AMN Information: AMN Protein, AMN Antibody and AMN Gene

AMN Protein

AMN protein function

Necessary for efficient absorption of vitamin B12 (PubMed:12590260, PubMed:14576052). Required for normal CUBN-mediated protein transport in the kidney. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity). {ECO:0000250|UniProtKB:Q99JB7, ECO:0000269|PubMed:14576052, ECO:0000305|PubMed:12590260}.

AMN protein expression

Tissue specificity

Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes.

AMN protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    453.00
  • Mass (KDa)
    47.00

AMN Antibody

There are 2 AMN antibodies which are validated in multiple tissues with various applications, including IHC-P. There are 2 AMN antibody for IHC-P. Among all these AMN antibodies, there are 2 anti-AMN rabbit polyclonal antibodies . All the AMN anbodies are produced in house and all are in stock. AMN antibody customerized service is available.

AMN Gene

AMN gene / cDNA is a protein-coding gene which located on 14q32.32. The AMN gene is conserved in chimpanzee, cow, mouse, rat, chicken, zebrafish, and frog.224 organisms have orthologs with human gene AMN.