ARH3 Information: ARH3 Protein, ARH3 Antibody and ARH3 Gene

ARH3 Protein

ARH3 protein function

Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria.

ARH3 protein expression

Tissue specificity

Ubiquitous.

ARH3 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    363.00
  • Mass (KDa)
    38.00

ARH3 Gene

ADPRHL2 cDNA / gene is a gene with protein product which located on 1p34.3. The ADPRHL2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, and frog. 243 organisms have orthologs with human gene ADPRHL2.