B7-H4 Gene Sequence, Family, Fuction and Expression Information
B7-H4 cDNA / Gene Overview
VTCN1 gene / cDNA is a protein-coding gene which located on 1p13.1-p12. The VTCN1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.209 organisms have orthologs with human gene VTCN1.
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
B7-H4 cDNA / Gene Sequence
LOCUS NM_024626 2652 bp mRNA linear PRI 29-JUL-2018
Homo sapiens V-set domain containing T cell activation inhibitor 1 (VTCN1), transcript variant 1, mRNA.
This sequence information is just for reference only.