Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
C1orf80 protein expression
Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle.
AIDA cDNA / gene is a gene with protein product which located on 1q41. The AIDA gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, and zebrafish. 240 organisms have orthologs with human gene AIDA.