C8A Gene Sequence, Family, Fuction and Expression Information
C8A cDNA / Gene Overview
C8A cDNA / gene is a gene with protein product which located on 1p32.2. The C8A gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 242 organisms have orthologs with human gene C8A.
C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008]
C8A cDNA / Gene Sequence
HUMC8AS 2397 bp mRNA linear PRI 07-NOV-1994
Human complement protein C8 alpha subunit mRNA, complete cds.
This sequence information is just for reference only.