Carbonic anhydrase II Gene Sequence, Family, Fuction and Expression Information

Carbonic anhydrase II cDNA / Gene Overview

CA2 gene / cDNA is a protein-coding gene which located on 8q21.2. The CA2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.133 organisms have orthologs with human gene CA2.

Carbonic anhydrase II cDNA / Gene Function

The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Carbonic anhydrase II cDNA / Gene Sequence

LOCUS
LOCUS NM_000067 1666 bp mRNA linear PRI 22-JUL-2018
DEFINITION
Homo sapiens carbonic anhydrase 2 (CA2), transcript variant 1, mRNA.
ACCESSION
NM_000067
VERSION
NM_000067.2

This sequence information is just for reference only.

Carbonic anhydrase II Family & Reagents

Gene family

Carbonic anhydrase II Gene family reagents (Carbonic anhydrases)

Approved Symbol Reagent list
CA10
CA13
CA3
CA5A
CA7
CA9
Approved Symbol Reagent list
CA12
CA14
CA4
CA5B
CA8
   

Carbonic anhydrase II cDNA / Gene Alias

  • CAII
  • CA-II
  • Car2

Carbonic anhydrase II cDNA / Gene Expression

Biased expression in stomach (RPKM 493.8), colon (RPKM 349.1) and 8 other tissues