Carbonic anhydrase II Protein Overview: Sequence, Structure, Function and Protein Interaction

Carbonic anhydrase II Protein Overview

Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. For background information on the CA family, see 114800.

Carbonic anhydrase II protein family

Belongs to the alpha-carbonic anhydrase family.

Carbonic anhydrase II protein name

Recommended name
Carbonic anhydrase 2
Aliases
CAII, CA-II, Car2
Alternative name
Carbonate dehydratase II Carbonic anhydrase C CAC Carbonic anhydrase II CA-II

Carbonic anhydrase II Protein Sequence

Species Human Carbonic anhydrase II protein
Length 260
Mass (Da) 29246
Sequence Human Carbonic anhydrase II protein sequence
Species Mouse Carbonic anhydrase II protein
Length 260
Mass (Da) 29033
Sequence Mouse Carbonic anhydrase II protein sequence
Species Rat Carbonic anhydrase II protein
Length 260
Mass (Da) 29114
Sequence Rat Carbonic anhydrase II protein sequence

Carbonic anhydrase II Protein Molecular Weight & PI

Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 2-260 Carbonic anhydrase 2.

Molecular weight (Da)

29114.86

Theoretical pI

6.86

Carbonic anhydrase II Protein Structure

ALTERING THE MOUTH OF A HYDROPHOBIC POCKET. STRUCTURE AND KINETICS OF HUMAN CARBONIC ANHYDRASE II MUTANTS AT RESIDUE VAL-121
Deposited
1991-10-01   Released:  1992-10-15
Deposition Author(s)
Nair, S.K., Christianson, D.W.
Organism(s)
Homo sapiens
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.4000 Å
12CA From PDB

Human Carbonic anhydrase II protein Secondary structure

Carbonic anhydrase II Protein Interaction

Recombinant Carbonic anhydrase II Protein Feature

Carbonic anhydrase II Protein, Human, Recombinant (His Tag)

High Purity
> 96 % as determined by SDS-PAGE
Low Endotoxin
Please contact us for more information.
High Activity
Measured by its esterase activity. The specific activity is >150 pmoles/min/μg .

Recombinant Carbonic anhydrase II protein citations

Title
5-[2-(N-(substituted phenyl) acetamide)] amino-1, 3, 4-thiadiazole -2-sulfonamides as selective carbonic anhydrase II inhibitor with neuroprotective effects
Year
2020
Author
Zhang, J;Jiang, C;Shi, J;Liao, L;Zhang, L;Liu, J;Wang, Y;Lao, Y;
Journal
ChemMedChem

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