CD226 Protein Overview: Sequence, Structure, Function and Protein Interaction

CD226 Protein Overview

CD226 belongs to the immunoglobulin (Ig) superfamily and is expressed on the majority of natural killer (NK) cells, T cells, monocytes, and platelets. Through its interaction with various ligands, including LFA1 (see 153370), CD155 (PVR; 173850), and CD112 (PVRL2; 600798), CD226 plays an important role in T cell- and NK cell-mediated recognition and lysis of tumor cells (summary by Iguchi-Manaka et al., 2008).

CD226 protein name

Recommended name
CD226 antigen
Alternative name
DNAX accessory molecule 1 DNAM-1 CD antigen CD226

CD226 Gene family protein

CD226 Protein Sequence

Species Human CD226 protein
Length 336
Mass (Da) 38614
Sequence Human CD226 protein sequence
Species Mouse CD226 protein
Length 333
Mass (Da) 38063
Sequence Mouse CD226 protein sequence
Mass (Da)

CD226 Protein Molecular Weight & PI

CD226 antigen precursor (DNAX accessory molecule 1) (DNAM-1) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 19-336 CD226 antigen.

Molecular weight (Da)


Theoretical pI


CD226 Protein Interaction

Recombinant CD226 Protein Feature

CD226 Protein, Human, Recombinant (ECD, His Tag)

High Purity
> 97 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
High Activity
Measured by its binding ability in a functional ELISA . Immobilized human CD226 at 2 μg/ml (100 μl/well) can bind human CD112 with a linear range of 6.4-800 ng/ml.

Bulk Order of Recombinant CD226 Protein

Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the website, our customer specialist will get back to you in 24 hours by email.

Custom Recombinant Protein Production Service Features

  • Over 10 years' experience for 6000+ recombinant proteins production.
  • One-stop service from gene synthesis and vector construction to protein expression and purification.
  • Multiple protein expression systems: bacterial, yeast, baculovirus-insect and mammalian expression system.
  • Multiple purification systems (30+) to choose.
  • High R & D ability with over 1000 new proteins per year and quick problem-solving ability.
  • Close to 100 bioreactors with various volume between 2-1000 L to guarantee high-throughput and large-scale production.

Custom Recombinant Protein Production Service Advantages

  • High-efficiency expression vectors
  • High cell density culturing
  • Proprietary medium formulation
  • >6000 proteins expression and purification experience
  • High-efficiency expression vectors
  • High cell density culturing

Recombinant Protein Production Service Description

We offer one-stop services for recombinant protein production using our advanced protein expression platform technologies. Our full services include protein gene synthesis, protein codon optimization, protein expression vector design, large scale cell culture and fermentation, protein purification, and protein quality control testing. We offer significant cost saving advantages and record speed in protein expression and bulk production. We also have extensive experiences and expertise in handling various types of recombinant protein purification projects, with or without purification tags.