CD83 Gene Sequence, Family, Fuction and Expression Information

CD83 cDNA / Gene Overview

CD83 gene / cDNA is a protein-coding gene which located on 6p23. The CD83 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.217 organisms have orthologs with human gene CD83.

CD83 cDNA / Gene Function

The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

CD83 cDNA / Gene Sequence

LOCUS
LOCUS NM_001040280 2475 bp mRNA linear PRI 23-JUN-2018
DEFINITION
Homo sapiens CD83 molecule (CD83), transcript variant 2, mRNA.
ACCESSION
NM_001040280
VERSION
NM_001040280.1

This sequence information is just for reference only.

CD83 Family & Reagents

CD83 Gene family reagents (CD molecules)

Approved Symbol Reagent list
ALCAM
IL10RA
CLEC12A
CD82
CD96
CD6
NRP1
IFNGR1
IL4R
GP1BB
Approved Symbol Reagent list
TNFRSF1A
ICAM2
THY1
SELE
TNFRSF10D
ART4
BST1
TNFRSF1B
ART1
LILRB1

CD83 Gene family reagents (V-set domain containing)

Approved Symbol Reagent list
BTN3A2
SCN2B
NECTIN2
CD276
CD86
HAVCR1
CADM3
NCR2
IGSF3
CEACAM6
Approved Symbol Reagent list
Vsir
SIRPG
CADM2
CADM1
CD8A
SIGLEC6
CD300C
F11R
IGSF8
SLAMF7

CD83 cDNA / Gene Alias

  • BL11
  • HB15

CD83 cDNA / Gene Expression

Broad expression in bone marrow (RPKM 72.2), lymph node (RPKM 25.8) and 14 other tissues