CDK2 Gene Sequence, Family, Fuction and Expression Information

CDK2 cDNA / Gene Overview

CDK2 gene / cDNA is a protein-coding gene which located on 12q13.2. The CDK2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.188 organisms have orthologs with human gene CDK2.

CDK2 cDNA / Gene Function

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

CDK2 cDNA / Gene Sequence

LOCUS
LOCUS NM_001290230 2121 bp mRNA linear PRI 15-JUL-2018
DEFINITION
Homo sapiens cyclin dependent kinase 2 (CDK2), transcript variant 3, mRNA.
ACCESSION
NM_001290230
VERSION
NM_001290230.1

This sequence information is just for reference only.

CDK2 Family & Reagents

CDK2 Gene family reagents (Cyclin dependent kinases)

Approved Symbol Reagent list
CDK1
CDK4
CDKL2
Approved Symbol Reagent list
CDK16
CDK5
   

CDK2 cDNA / Gene Expression

Ubiquitous expression in placenta (RPKM 29.3), bone marrow (RPKM 14.9) and 24 other tissues