CDK2 Gene Sequence, Family, Fuction and Expression Information
CDK2 cDNA / Gene Overview
CDK2 gene / cDNA is a protein-coding gene which located on 12q13.2. The CDK2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.188 organisms have orthologs with human gene CDK2.
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
CDK2 cDNA / Gene Sequence
LOCUS NM_001290230 2121 bp mRNA linear PRI 15-JUL-2018